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Antiphospholipid Syndrome

Unique Accuracy in APS Diagnostics.

Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by recurrent thrombosis, pregnancy morbidity, and a variety of other non-thrombotic manifestations. Patients are characterized by persistent antibodies against phospholipids and/or phospholipid-binding plasma proteins, which are responsible for the hypercoagulability of the blood. The classical APS criteria are based on the presence of lupus anticoagulant (LA), anticardiolipin (aCL), and anti-β2 glycoprotein I (anti-β2GPI) antibodies combined with clinical events such as thrombosis or pregnancy complications. Non-criteria APS antibodies, including anti-phosphatidylserine/prothrombin (aPS/PT) and anti-annexin V, are increasingly recognized for identifying patients with APS manifestations not captured by the traditional criteria.

Antiphospholipid syndrome can lead to serious consequences, including recurrent blood clots, pregnancy loss, organ damage, and long-term disability if not properly managed.

Knowledge & Science

Instruments for diagnosing Antiphospholipid Syndrome

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Carefully read the instructions in the reagent package inserts and instrument manuals.