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von Willebrand Disease

A bleeding disorder of genetic origin, or sometimes acquired, that affects blood clotting.

Von Willebrand disease (VWD) is a genetic bleeding disorder caused by a deficiency or dysfunction of von Willebrand factor (VWF), a key protein involved in blood clotting. VWF is a multimeric protein that enables platelets to adhere to and aggregate at sites of blood vessel injury. It also binds to factor VIII and forms a crucial bridge between platelet receptors and exposed subendothelial collagen, supporting the formation of an effective clot.

Von Willebrand Disease cannot be cured, but effective treatments and self‑care help most people lead active lives. Accurate subtype diagnosis is essential for guiding optimal management.

Knowledge & Science

Instruments for diagnosing von Willebrand Disease

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Please contact your local Sebia representative. Information intended for healthcare professionals.
Carefully read the instructions in the reagent package inserts and instrument manuals.