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From Pathology to Practice: How Oligoclonal Bands Enhance Neurological Disorders Diagnosis

This webinar is presented in English.

Publié: 2/12/2025 | Modifié: 8/19/2026

Abstract

This webinar aims to elucidate the fundamental role of cerebrospinal fluid (CSF) as a diagnostic tool in differentiating Multiple Sclerosis (MS) from other neurological disorders.

In recent years, diagnostic criteria for MS have evolved to enable earlier diagnosis and facilitate timely interventions. However, diagnosing MS remains challenging due to the high prevalence of conditions that mimic MS clinically and radiologically.

This webinar will delve into the specific components of CSF, with a particular focus on oligoclonal bands and free kappa light chains, and their correlation with the underlying pathophysiology of the disease. The ultimate goal is to gain a deeper understanding of how CSF analysis contributes to the differential diagnosis and management of MS.

What will you learn?

  • The Role of CSF in Multiple Sclerosis Diagnosis

    Understand how cerebrospinal fluid (CSF) analysis helps support the diagnosis of Multiple Sclerosis and differentiate it from other neurological disorders.

  • Advances in MS Diagnostic Criteria

    Explore the evolution of MS diagnostic criteria and their impact on earlier diagnosis and timely patient management.

  • Recognizing and Differentiating MS Mimics

    Learn about the conditions that can resemble MS clinically and radiologically, and the challenges they pose in the diagnostic process.

  • The Diagnostic Value of Oligoclonal Bands and Free Kappa Light Chains

    Discover the significance of these key CSF biomarkers and their contribution to improving diagnostic accuracy.

  • Using CSF Analysis to Guide Patient Management

    Gain insight into how CSF findings reflect disease pathophysiology and support differential diagnosis and clinical decision-making.

OCB detection demonstrates high diagnostic sensitivity and remains the gold standard
Dr. Maria Di Cristinzi Neurologist, University of Florence, Italy

About Dr. Maria Di Cristinzi

Maria Di Cristinzi is a neurologist with expertise in Multiple Sclerosis (MS).

She completed her medical degree at San Raffaele Vita-Salute University in Milan in Italy. Subsequently, she attended a residency in Neurology at the University of Florence, where she is currently pursuing a PhD in Neuroscience. Her research grant is focusing on the impact of disease-modifying treatments on the immune system in MS.

Dr. Di Cristinzi’s research special interests include the pathophysiology of MS, and the clinical and MRI evaluation of disease modifying treatment.

Dr. Maria Di Cristinzi

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