Compare immunotyping and immunofixation for M-protein detection
Understand the similarities and differences in performance between IT and IF for identifying and characterizing monoclonal proteins.
Performance of Immunotyping vs. Immunofixation for the Detection of Monoclonal Gammopathies
This webinar is presented in English.
Abstract
Serum immunofixation (IF) is routinely used in clinical laboratories to confirm the presence of an M-protein and determine its isotype. For laboratories looking for more of an automated method for the detection of M-proteins, immunotyping (IT) by capillary electrophoresis is also FDA-approved to confirm the presence of M-proteins and determine its isotype.
In this webinar, Dr. Katie Thoren will discuss a recent study comparing the performance of immunotyping to immunofixation for the detection of M-proteins. She will show that reviewer training and experience are critical to the correct interpretation of IT results and that the analytical and clinical sensitivity is similar to IF for the detection of M-proteins. Dr. Thoren will present the data, review the limitations of each test and discuss potential strategies for mitigating these limitations.
What will you learn?
Evaluate the impact of reviewer training on test interpretation
Learn how experience and training influence the accuracy and reliability of immunotyping result assessment.
Understand the strengths and limitations of each method
Review the analytical and clinical considerations of IT and IF, including potential limitations and mitigation strategies for routine laboratory practice.
Training is really critical to the sensitivity of immunotyping
About Dr. Katie Thoren
Dr. Katie Thoren, PhD, DABCC, is an Assistant Attending Clinical Chemist in the Department of Laboratory Medicine at Memorial Sloan Kettering Cancer Center. She specializes in clinical chemistry and laboratory diagnostics, with expertise in protein immunology testing and the detection and monitoring of monoclonal gammopathies. Through her work, Dr. Thoren supports the development and evaluation of advanced laboratory methods that improve the accuracy, efficiency, and clinical utility of diagnostic testing for patients with plasma cell disorders.
Tests associated with this resource
Deepen your expertise with additional webinars
Educational Webinar with Prof. Alessandro Gozzetti, MD, PhD
Educational Webinar with Prof. Giovanni PALLADINI, PhD
Educational Webinar with Katie Thoren, PhD
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